Recombinant人RGS16 protein (ab93733)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT
    • 氨基酸1 to 202
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab93733 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, PBS, 100mM Sodium chloride, pH 7.4

常规信息

  • 别名
    • A28 RGS14
    • A28 RGS14P
    • A28-RGS14P
    • HGNC:9997
    • hRGS-r
    • OTTHUMP00000033147
    • Regulator of G protein signaling 16
    • Regulator of G protein signalling 16
    • Regulator of G-protein signaling 16
    • Retinal-specific RGS
    • Retinally abundant regulator of G protein signaling
    • Retinally abundant regulator of G-protein signaling
    • RGS 16
    • RGS R
    • RGS-R
    • Rgs14
    • RGS16
    • RGS16_HUMAN
    • RGSR
    see all
  • 功能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
  • 组织特异性Abundantly expressed in retina with lower levels of expression in most other tissues.
  • 序列相似性Contains 1 RGS domain.
  • 翻译后修饰Palmitoylated on Cys-2 and/or Cys-12.
    Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.
  • Information by UniProt

Recombinant Human RGS16 protein 图像

  • 15% SDS Page analysis of 3ug ab93733

Recombinant Human RGS16 protein (ab93733)参考文献

ab93733 has not yet been referenced specifically in any publications.

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