Recombinant人Retinoic Acid Receptor beta protein (ab82202)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab82202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

常规信息

  • 别名
    • HAP
    • HBV-activated protein
    • NR1B2
    • Nuclear receptor subfamily 1 group B member 2
    • RAR B
    • RAR beta
    • RAR epsilon
    • RAR-beta
    • RAR-epsilon
    • RARB
    • RARB_HUMAN
    • Retinoic acid receptor beta
    • Retinoic acid receptor beta 2
    • Retinoic acid receptor beta 4
    • Retinoic acid receptor beta 5
    • Retinoic acid receptor beta polypeptide
    • RRB2
    see all
  • 功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
  • 疾病相关Microphthalmia, syndromic, 12
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 细胞定位Cytoplasm and Nucleus.
  • Information by UniProt

Recombinant Human Retinoic Acid Receptor beta protein (ab82202)参考文献

ab82202 has not yet been referenced specifically in any publications.

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