Recombinant人RAP2B protein (ab88159)

概述

描述

  • 性质Recombinant
  • 来源Saccharomyces cerevisiae
  • 氨基酸序列
    • 种属Human
    • 序列MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSP SVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI IRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNK ASVDELFAEIVRQMNYAAQPNGDEGCCSACVIL

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技术指标

Our Abpromise guarantee covers the use of ab88159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    purified by affinity chromatography
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5

常规信息

  • 别名
    • MGC20484
    • RAP 2B
    • RAP2A
    • Rap2b
    • RAP2B member of RAS oncogene family
    • RAP2B_HUMAN
    • Ras family small GTP binding protein RAP2B
    • Ras related protein RAP 2B
    • Ras related protein RAP2B
    • Ras-related protein Rap-2b
    • Small GTP binding protein
    see all
  • 功能Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
  • 组织特异性Expressed in red blood cells (at protein level).
  • 序列相似性Belongs to the small GTPase superfamily. Ras family.
  • 结构域The effector domain mediates the interaction with RUNDC3A.
  • 翻译后修饰Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
  • 细胞定位Recycling endosome membrane. Associated with red blood cells-released vesicles.
  • Information by UniProt

Recombinant Human RAP2B protein (ab88159)参考文献

ab88159 has not yet been referenced specifically in any publications.

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