Recombinant人RAP1B protein (ab103049)

概述

  • 产品名称Recombinant人RAP1B protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP61224
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMREYKLVVLGSGGVGKSALTVQFVQGIFVE KYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFAL VYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQ GQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS C
    • 分子量23 kDa including tags
    • 氨基酸1 to 181
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab103049 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • GTP-binding protein smg p21B
    • K-REV
    • OK/SW-cl.11
    • RAL1B
    • rap1b
    • RAP1B member of RAS oncogene family
    • RAP1B_HUMAN
    • Ras family small GTP binding protein RAP1B
    • RAS related protein RAP1B
    • Ras-related protein Rap-1b
    • Small GTP binding protein
    see all
  • 功能GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.
  • 序列相似性Belongs to the small GTPase superfamily. Ras family.
  • 细胞定位Cell membrane. Cytoplasm > cytosol. Cell junction. May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.
  • Information by UniProt

Recombinant Human RAP1B protein 图像

  • 15% SDS-PAGE analysis of 3µg ab103049

Recombinant Human RAP1B protein (ab103049)参考文献

ab103049 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"