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Our Abpromise guarantee covers the use of ab90203 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The mutation E70A results in inhibition of the guanine exchange reaction mediated by RCC1, the guanine nucleotide exchange factor (GEF) for Ran.Protein preparation is 85% GDP-loaded, measured by HPLC.
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 5mM Magnesium chloride, 20mM Potassium phosphate, 1mM DTE (1, 4-Dithioerythritol), pH 7.4
ab90203 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"