- 来源Escherichia coli
- 序列MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 95
ab78880 is purified using conventional chromatography techniques.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 20% Glycerol, 20mM Tris, pH 8.0
- CASP2 and RIPK1 domain containing adaptor with death domain
- Caspase and RIP adapter with death domain
- Caspase and RIP adaptor with death domain
- 功能Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
- 组织特异性Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
- 序列相似性Contains 1 CARD domain.
Contains 1 death domain.
- 结构域Contains a death domain involved in the binding of RIP protein.
The CARD domain mediates the interaction with caspase-2.
Information by UniProt
Recombinant Human RAIDD protein 图像
Recombinant Human RAIDD protein (ab78880)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"