Recombinant人RAB35 protein (ab113586)

概述

  • 产品名称Recombinant人RAB35 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ15286
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMARDYDHLFKLLIIGDSGVGKSSLLLRFAD NTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRG THGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVV ETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQ QQQQNDVVKLTKNSKRKKRCC
    • 分子量25 kDa including tags
    • 氨基酸1 to 201
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab113586 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • GTP binding protein RAY
    • GTP-binding protein RAY
    • H ray
    • OTTHUMP00000240256
    • OTTHUMP00000240257
    • OTTHUMP00000240258
    • OTTHUMP00000240259
    • RAB1C
    • Rab35
    • RAB35 member RAS oncogene family
    • RAB35, member RAS oncogene family
    • RAB35_HUMAN
    • Ras related protein Rab 1C
    • Ras related protein rab 1c (GTP binding protein ray)
    • Ras related protein Rab35
    • Ras-related protein Rab-1C
    • Ras-related protein Rab-35
    • RAY
    see all
  • 功能In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge.
  • 序列相似性Belongs to the small GTPase superfamily. Rab family.
  • 细胞定位Cell membrane. Membrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Endosome. Melanosome. Present on sorting endosomes and endosomal tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Recombinant Human RAB35 protein 图像

  • 15% SDS-PAGE analysis of 3 µg ab113586.

Recombinant Human RAB35 protein (ab113586)参考文献

ab113586 has not yet been referenced specifically in any publications.

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