重组人PYGL蛋白(ab202149)
Key features and details
- Expression system: Escherichia coli
- Purity: > 80% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人PYGL蛋白 -
纯度
> 80 % SDS-PAGE.
ab202149 was purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMGSEFELRRQASMAKPLTDQEKRRQISIRG IVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRW IRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGL DIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFN QKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWID TQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVL DRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFG STRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEL TQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVAL FPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKV FKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQ LTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQV KRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAK MIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQIS TAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDD VAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIINMLFY HDRFKVFADYEAYVKCQDKVSQLYMNPKAWNMVLKNIAASGKFSSDRTIK EYAQNIWNVEPSDLKISLSNESNKVNGN -
预测分子量
101 kDa including tags -
氨基酸
1 to 847 -
标签
His tag N-Terminus -
额外的序列信息
NP_002854.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab202149 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 30% Glycerol (glycerin, glycerine), 0.02% DTT, 69% PBS
常规信息
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别名
- Glycogen phosphorylase
- Glycogen phosphorylase L
- Glycogen phosphorylase liver
see all -
功能
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. -
疾病相关
Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700]. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected. -
序列相似性
Belongs to the glycogen phosphorylase family. -
翻译后修饰
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab202149 尚未被引用在任何文献中。