Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Phosphoinositide lipid phosphatase
protein tyrosine phosphatase mitochondrial 1
Protein-tyrosine phosphatase mitochondrial 1
pten like phosphatase
功能Protein phosphatase that specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.
序列相似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain.
细胞定位Mitochondrion inner membrane. Associated with the inner membrane.