Recombinant人PTPIA2 / PTPRN protein (ab42590)

概述

  • 产品名称
    Recombinant人PTPIA2 / PTPRN protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 氨基酸
      693 to 979

技术指标

Our Abpromise guarantee covers the use of ab42590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Phosphatase Activity

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Liquid
  • 补充说明


    This protein may be useful for the study of enzyme kinetics, regulation, and to dephosphorylate target substrates.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 75mM Sodium chloride, 25mM Tris HCl, 2mM EDTA, 10mM Glutathione, 1mM DTT, pH 8.0

常规信息

  • 别名
    • CA 512
    • FLJ16131
    • IA 2
    • IA 2/PTP
    • IA2
    • IA2/PTP
    • ICA 3
    • ICA 512
    • ICA3
    • ICA512
    • Islet cell antigen 2
    • Islet cell antigen 512
    • Islet cell autoantigen 3
    • Protein tyrosine phosphatase like N
    • Protein tyrosine phosphatase like N precursor
    • Protein tyrosine phosphatase receptor type N
    • PTP IA 2
    • PTP IA-2
    • PTP IA2
    • PTPIA 2
    • PTPN
    • Ptprn
    • PTPRN protein
    • PTPRN_HUMAN
    • R PTP N
    • R-PTP-N
    • Receptor type tyrosine protein phosphatase like N
    • Receptor-type tyrosine-protein phosphatase-like N
    • RPTPN
    see all
  • 功能
    Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
  • 组织特异性
    Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
  • 序列相似性
    Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰
    Appears to undergo multiple proteolytic cleavage at consecutive basic residues.
  • 细胞定位
    Membrane. Neuroendocrine secretory granules.
  • Information by UniProt

Recombinant Human PTPIA2 / PTPRN protein (ab42590)参考文献

ab42590 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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