重组人ICA 512/PTPRN蛋白(ab42590)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Phosphatase Activity
描述
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产品名称
重组人ICA 512/PTPRN蛋白 -
纯度
> 95 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
59 kDa including tags -
氨基酸
693 to 979 -
标签
GST tag N-Terminus
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技术指标
Our Abpromise guarantee covers the use of ab42590 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Phosphatase Activity
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形式
Liquid -
补充说明
This protein may be useful for the study of regulation, and to dephosphorylate target substrates. It seems to lack intrinic enzyme activity.
Previously labelled as PTPIA2 / PTPRN.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.307% Glutathione, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.395% Tris HCl, 0.05% Tween, 0.0584% EDTA, 50% Glycerol (glycerin, glycerine), 0.435% Sodium chloride
常规信息
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别名
- CA 512
- FLJ16131
- IA 2
see all -
功能
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. -
组织特异性
Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. -
序列相似性
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain. -
翻译后修饰
Appears to undergo multiple proteolytic cleavage at consecutive basic residues. -
细胞定位
Membrane. Neuroendocrine secretory granules. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab42590 尚未被引用在任何文献中。