重组人PTP4A3/PRL-R蛋白(ab87716)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE, WB
描述
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产品名称
重组人PTP4A3/PRL-R蛋白 -
纯度
> 95 % SDS-PAGE.
ab87716 is purified using conventional chromatography techniques. Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method). -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVSYKHMRFL ITHNPTNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK DGITVVDWPF DDGAPPPGKV VEDWLSLVKA KFCEAPGSCV AVHCVAGLGR APVLVALALI ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF KDPHTHKTRC CVM
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab87716 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Western blot
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形式
Liquid -
补充说明
Previously labelled as PTP4A3.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)
常规信息
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别名
- Potentially prenylated protein tyrosine phosphatase
- PRL 3
- PRL R
see all -
功能
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. -
组织特异性
Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. -
序列相似性
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain. -
翻译后修饰
Farnesylated. Farnesylation is required for membrane targeting. -
细胞定位
Cell membrane. Early endosome. - Information by UniProt
图片
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15% SDS-PAGE showing ab87716 at approximately 21.6kDa (3µg).
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All lanes : Anti-PTP4A3/PRL-R antibody (ab82568) at 1 µg/ml
Lane 1 :Recombinant Human PTP4A3/PRL-R protein (ab87716) at 0.01 µg
Lane 2 :Recombinant Human PTP4A3/PRL-R protein (ab87716) at 0.1 µg
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Exposure time: 20 seconds
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab87716 尚未被引用在任何文献中。