Recombinant人PTGES2 protein (ab107954)

概述

  • 产品名称Recombinant人PTGES2 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionA6NHH0
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFG AVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKD RPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAIT EASPAH
    • 分子量24 kDa including tags
    • 氨基酸1 to 206
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab107954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    ab107954 was purified by using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

常规信息

  • 别名
    • C9orf15
    • FLJ14038
    • Gamma interferon activated transcriptional element binding factor 1
    • GATE binding factor 1
    • GBF 1
    • GBF1
    • Membrane associated prostaglandin E synthase 2
    • MGC11289
    • Microsomal prostaglandin E synthase 2
    • mPGES 2
    • mPGES-2
    • PGES2
    • PGES2_HUMAN
    • Prostaglandin E synthase 2
    • Prostaglandin E synthase 2 truncated form
    • PTGES 2
    • PTGES2
    see all
  • 功能Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear.
  • 组织特异性Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer.
  • 通路Lipid metabolism; prostaglandin biosynthesis.
  • 序列相似性Belongs to the GST superfamily.
    Contains 1 glutaredoxin domain.
    Contains 1 GST C-terminal domain.
  • 细胞定位Golgi apparatus membrane and Cytoplasm > perinuclear region. Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
  • Information by UniProt

Recombinant Human PTGES2 protein 图像

  • 15% SDS-PAGE analysis of ab107954 (3 µg).

Recombinant Human PTGES2 protein (ab107954)参考文献

ab107954 has not yet been referenced specifically in any publications.

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