Recombinant人PTBP1 protein (ab114379)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      KKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGK NQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQ
    • 分子量
      37 kDa including tags
    • 氨基酸
      45 to 144

技术指标

Our Abpromise guarantee covers the use of ab114379 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • 57 kDa RNA binding protein PPTB 1
    • 57 kDa RNA-binding protein PPTB-1
    • Heterogeneous nuclear ribonucleoprotein I
    • Heterogeneous Nuclear Ribonucleoprotein Polypeptide I
    • hnRNP I
    • HNRNP-I
    • HNRNPI
    • HNRPI
    • MGC10830
    • MGC8461
    • Polypyrimidine tract binding protein
    • Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I)
    • Polypyrimidine Tract Binding Protein 1
    • Polypyrimidine tract-binding protein 1
    • pPTB
    • PTB
    • PTB 1
    • PTB 2
    • PTB 3
    • PTB 4
    • PTB T
    • PTB1
    • PTB2
    • PTB3
    • PTB4
    • PTBP 1
    • PTBP1
    • PTBP1_HUMAN
    • PTBT
    • RNA Binding Protein
    see all
  • 功能
    Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
  • 序列相似性
    Contains 4 RRM (RNA recognition motif) domains.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • ab114379 on 12.5% SDS-PAGE stained with Coomassie Blue.

文献

ab114379 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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