Recombinant人PSMB5 protein (ab101825)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP28074
    • 种属Human
    • 序列MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMTTTLAFKFRHGVI VAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQC RIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYY VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQA TYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
    • 分子量27 kDa including tags
    • 氨基酸60 to 263
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab101825 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • DKFZp459C139
    • EC 3.4.25.1
    • LMPX
    • Macropain epsilon chain
    • MB1
    • MGC104214
    • MGC118075
    • MGC134464
    • Multicatalytic endopeptidase complex epsilon chain
    • Proteasome (prosome, macropain) subunit, beta type, 5
    • Proteasome beta 5 subunit
    • Proteasome catalytic subunit 3
    • Proteasome chain 6
    • Proteasome epsilon chain
    • Proteasome subunit beta type-5
    • Proteasome subunit MB1
    • Proteasome subunit X
    • Proteasome subunit, beta type, 5
    • Proteasome subunit, beta-5
    • PSB5_HUMAN
    • PSMB5
    • PSX large multifunctional protease X
    • X
    see all
  • 功能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the chymotrypsin-like activity of the proteasome and is one of the principal target of the proteasome inhibitor bortezomib. May catalyze basal processing of intracellular antigens. Plays a role in the protection against oxidative damage throught the Nrf2-ARE pathway.
  • 序列相似性Belongs to the peptidase T1B family.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human PSMB5 protein 图像

  • 15% SDS-PAGE analysis of ab101825 (3µg)

Recombinant Human PSMB5 protein (ab101825)参考文献

ab101825 has not yet been referenced specifically in any publications.

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