Recombinant人Protein phosphatase inhibitor 1 (ab78756)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH

技术指标

Our Abpromise guarantee covers the use of ab78756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab78756 is purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Tris, 1mM EDTA, 1mM DTT, 0.1mM PMSF, pH 8.0

常规信息

  • 别名
    • I 1
    • I-1
    • I1
    • Inhibitor 1
    • IPP 1
    • IPP-1
    • IPP1
    • Ppp1r1a
    • PPR1A_HUMAN
    • Protein phosphatase 1 regulatory (inhibitor) subunit 1A
    • Protein phosphatase 1 regulatory subunit 1A
    • Protein phosphatase inhibitor 1
    see all
  • 功能Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
  • 序列相似性Belongs to the protein phosphatase inhibitor 1 family.
  • 翻译后修饰Phosphorylation of Thr-35 is required for activity.
  • Information by UniProt

Recombinant Human Protein phosphatase inhibitor 1 图像

  • 15% SDS-PAGE showing ab78756 at approximately 20kDa (3µg).

Recombinant Human Protein phosphatase inhibitor 1 (ab78756)参考文献

ab78756 has not yet been referenced specifically in any publications.

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