Recombinant人Protein phosphatase inhibitor 1 (ab117672)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEI DEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEE PEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKE PSTKEPSTHIPPLDSKGANSVLEHHHHHH
    • 分子量
      20 kDa including tags
    • 氨基酸
      1 to 171
    • 标签
      His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab117672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    HPLC

  • 纯度
    > 90 % SDS-PAGE.
    ab117672 is purified by proprietary chromatographic techniques. Purity is greater than 90% as determined by RP-HPLC and SDS-PAGE.
  • 形式
    Liquid
  • 补充说明
    Although stable at 4°C for 4 weeks, ab117672 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.61% Tris, 0.03% EDTA, 0.002% PMSF, 10% Glycerol, 0.02% DTT

常规信息

  • 别名
    • I 1
    • I-1
    • I1
    • Inhibitor 1
    • IPP 1
    • IPP-1
    • IPP1
    • Ppp1r1a
    • PPR1A_HUMAN
    • Protein phosphatase 1 regulatory (inhibitor) subunit 1A
    • Protein phosphatase 1 regulatory subunit 1A
    • Protein phosphatase inhibitor 1
    see all
  • 功能
    Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
  • 序列相似性
    Belongs to the protein phosphatase inhibitor 1 family.
  • 翻译后修饰
    Phosphorylation of Thr-35 is required for activity.
  • Information by UniProt

文献

ab117672 has not yet been referenced specifically in any publications.

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