Recombinant人Protein Kinase D2 (ab60875)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab60875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 形式Liquid
  • 补充说明

    ab204856 (CREB peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • DKFZp586E0820
    • HSPC187
    • KPCD2_HUMAN
    • nPKC D2
    • nPKC-D2
    • PKD2
    • PRKD 2
    • Prkd2
    • Protein kinase D2
    • Serine/threonine protein kinase D2
    • Serine/threonine-protein kinase D2
    see all
  • 功能Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylation of Ser-876 correlates with the activation status of the kinase.
    Ser-706 is probably phosphorylated by PKC.
  • 细胞定位Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt

Recombinant human Protein Kinase D2 图像

  • Sample Kinase Activity Plot.
  • ab60875 on SDS-PAGE, MW ~130 kDa.

Recombinant human Protein Kinase D2 (ab60875)参考文献

ab60875 has not yet been referenced specifically in any publications.

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