Recombinant人Proteasome 20S LMP2 protein (ab105592)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP28065
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMTTIMAVEFDGGVVMGSDSRVSA GEAVV NRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELEE PPL VLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLTRQ P FAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGV IYLVTITAAGVDHRVILGNELPKFYDE
    • 分子量24 kDa including tags
    • 氨基酸21 to 219
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab105592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab105592 was purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • Beta1i
    • Large multifunctional peptidase 2
    • Large multifunctional protease 2
    • LMP 2
    • LMP2
    • Low molecular mass protein 2
    • Macropain chain 7
    • MGC70470
    • Multicatalytic endopeptidase complex chain 7
    • OTTHUMP00000062982
    • Proteasome (prosome macropain) subunit beta type 9
    • proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
    • Proteasome beta 9 subunit
    • Proteasome catalytic subunit 1i
    • Proteasome chain 7
    • Proteasome related gene 2
    • Proteasome subunit beta 6i
    • Proteasome subunit beta type 9
    • Proteasome subunit beta type-9
    • Proteasome subunit beta-1i
    • PSB9_HUMAN
    • PSMB 9
    • PSMB6i
    • PSMB9
    • Really interesting new gene 12 protein
    • RING 12
    • RING12
    • RING12 protein
    see all
  • 功能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
  • 序列相似性Belongs to the peptidase T1B family.
  • 发展阶段Highly expressed in immature dendritic cells (at protein level).
  • 翻译后修饰Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human Proteasome 20S LMP2 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab105592.

Recombinant Human Proteasome 20S LMP2 protein (ab105592)参考文献

ab105592 has not yet been referenced specifically in any publications.

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