Recombinant人Prosurfactant Protein C (ab114293)

概述

  • 产品名称Recombinant人Prosurfactant Protein C
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP11686
    • 种属Human
    • 序列MDVGSKEVLMESPPDYSAAPRGRFGIPRCPVHLKRLLIVVVVVVLIVVVI VGALLMGLHMSQKHTEMVLEMSIGAPEAQQRLALSEHLVTTATFSIGSTG LVVYDYQQLLIAYKPAPGTCCYIMKIAPESIPSLEALNRKVHNFQMECSL QAKPAVPTSKLGQAEGRDAGSAPSGGDPAFLGMAVNTLCGEVPLYYI
    • 分子量47 kDa including tags
    • 氨基酸1 to 197

技术指标

Our Abpromise guarantee covers the use of ab114293 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BRICD6
    • BRICHOS domain containing 6
    • PSP C
    • PSPC
    • PSPC_HUMAN
    • Pulmonary surfactant apoprotein 2
    • Pulmonary surfactant apoprotein PSP C
    • pulmonary surfactant apoprotein-2 SP-C
    • Pulmonary surfactant associated protein C
    • Pulmonary surfactant associated proteolipid SPL pVal
    • Pulmonary surfactant associated proteolipid SPL(Val)
    • Pulmonary surfactant protein SP5
    • Pulmonary surfactant-associated protein C
    • Pulmonary surfactant-associated proteolipid SPL(Val)
    • SFTP 2
    • SFTP2
    • SFTPC
    • SFTPC surfactant pulmonary associated protein C
    • SMDP2
    • SP 5
    • SP C
    • SP-C
    • SP5
    • SPC
    • Surfactant associated protein pulmonary 2
    • Surfactant protein c
    • Surfactant proteolipid SPL-pVal
    • Surfactant pulmonary associated protein C
    see all
  • 功能Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
  • 疾病相关Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2) [MIM:610913]; also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
    Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS) [MIM:267450]; also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'.
  • 序列相似性Contains 1 BRICHOS domain.
  • 细胞定位Secreted > extracellular space > surface film.
  • Information by UniProt

Recombinant Human Prosurfactant Protein C 图像

  • ab114293 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human Prosurfactant Protein C (ab114293)参考文献

ab114293 has not yet been referenced specifically in any publications.

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