来源 Escherichia coli
序列 MGSSHHHHHH SSGLVPRGSH MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF 技术指标
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
纯度 > 95
% SDS-PAGE. ab95291 was purified using conventional chromatography techniques.
Concentration information loading... 制备和贮存
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
功能 Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
组织特异性 Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
序列相似性 Belongs to the profilin family.
细胞定位 Cytoplasm > cytoskeleton.
Information by UniProt
Recombinant Human Profilin 2 protein 图像
Recombinant Human Profilin 2 protein (ab95291)参考文献
has not yet been referenced specifically in any publications.
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