概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY

技术指标

Our Abpromise guarantee covers the use of ab87760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab87760 is purified using conventional chromatography techniques.
  • 形式Liquid
  • 补充说明Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • Actin binding protein
    • ALS18
    • Epididymis tissue protein Li 184a
    • OTTHUMP00000125244
    • Pfn
    • PFN 1
    • PFN1
    • PROF1_HUMAN
    • Profilin I
    • Profilin-1
    • Profilin1
    • ProfilinI
    see all
  • 功能Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
  • 序列相似性Belongs to the profilin family.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human Profilin 1 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab87760.

Recombinant Human Profilin 1 protein (ab87760)参考文献

This product has been referenced in:
  • Zienkiewicz A  et al. Chip-based capillary electrophoresis profiling of olive pollen extracts used for allergy diagnosis and immunotherapy. Electrophoresis 35:2681-5 (2014). Read more (PubMed: 24888349) »
  • Caglayan E  et al. Profilin-1 is expressed in human atherosclerotic plaques and induces atherogenic effects on vascular smooth muscle cells. PLoS One 5:e13608 (2010). Read more (PubMed: 21049052) »

See all 2 Publications for this product

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