Recombinant人PPP2R5A protein (ab114910)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQ AELHPLPQLKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRAT LNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEP TLEASWPHIQLVYEFFLRFLESPDFRPSIAKRYIDQKFVQQLLELFDSED PRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELL EILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEE PLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENINKILPIMFASLY KISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELE REELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
    • 分子量
      80 kDa including tags
    • 氨基酸
      1 to 486

技术指标

Our Abpromise guarantee covers the use of ab114910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 2A5A_HUMAN
    • B56A
    • MGC131915
    • PP2A B subunit B' alpha isoform
    • PP2A B subunit B56 alpha isoform
    • PP2A B subunit isoform B''-alpha
    • PP2A B subunit isoform B56-alpha
    • PP2A B subunit isoform PR61-alpha
    • PP2A B subunit isoform R5-alpha
    • PP2A B subunit PR61 alpha isoform
    • PP2A B subunit R5 alpha isoform
    • PPP2R5A
    • PR61A
    • PR61alpha
    • Protein phosphatase 2 regulatory subunit B (B56) alpha isoform
    • Protein phosphatase 2 regulatory subunit B' alpha
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
    see all
  • 功能
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 组织特异性
    Widely expressed with the highest expression in heart and skeletal muscle.
  • 序列相似性
    Belongs to the phosphatase 2A regulatory subunit B56 family.
  • 翻译后修饰
    Phosphorylated on serine residues.
  • 细胞定位
    Cytoplasm. Nucleus. Chromosome > centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE showing ab114910 at approximately 79.57kDa.
    Stained with Coomassie Blue.

文献

ab114910 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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