Recombinant人PPP1R3A protein (ab116962)

概述

  • 产品名称Recombinant人PPP1R3A protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ16821
    • 种属Human
    • 序列PSEVPSQISKDNFLEVPNLSDSLCEDEEVTFQPGFSPQPSRRGSDSSEDI YLDTPSSGTRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHT
    • 分子量37 kDa including tags
    • 氨基酸3 to 101

技术指标

Our Abpromise guarantee covers the use of ab116962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle
    • Glycogen associated regulatory subunit of protein phosphatase 1
    • GM
    • PP1G
    • PPP1R3
    • PPP1R3A
    • PPR3A_HUMAN
    • Protein phosphatase 1 glycogen-associated regulatory subunit
    • Protein phosphatase 1 glycogen-targeting subunit, muscle
    • Protein phosphatase 1 regulatory subunit 3A
    • Protein phosphatase 1 regulatory subunit GM
    • protein phosphatase 1, regulatory (inhibitor) subunit 3A
    • Protein phosphatase 1, regulatory subunit 3
    • Protein phosphatase type-1 glycogen targeting subunit
    • RG1
    • Serine /threonine specific protein phosphatase
    • Type 1 protein phosphatase skeletal muscle glycogen targeting subunit
    see all
  • 功能Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
  • 组织特异性Skeletal muscle and heart.
  • 疾病相关Diabetes mellitus, non-insulin-dependent
  • 序列相似性Contains 1 CBM21 (carbohydrate binding type-21) domain.
  • 结构域The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
  • 翻译后修饰Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human PPP1R3A protein 图像

  • 12.5% SDS-PAGE showing ab116962 at approximately 36.52kDa stained with Coomassie Blue.

Recombinant Human PPP1R3A protein (ab116962)参考文献

ab116962 has not yet been referenced specifically in any publications.

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