Recombinant人PPIL2 protein (ab117682)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ13356-2
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGKRQHQKDK MYITCAEYTH FYGGKKPDLP QTNFRRLPFD HCSLSLQPFV YPVCTPDGIV FDLLNIVPWL KKYGTNPSNG EKLDGRSLIK LNFSKNSEGK YHCPVLFTVF TNNTHIVAVR TTGNVYAYEA VEQLNIKAKN FRDLLTDEPF SRQDIITLQD PTNLDKFNVS NFYHVKNNMK IIDPDEEKAK QDPSYYLKNT NAETRETLQE YKEFKGDEI LAATMKAPEK KKVDKLNAAH YSTGKVSASF TSTAMVPETT EAAAIDEDV LRYQFVKKKG YVRLHTNKGD LNLELHCDLT PKTCENFIRL CKKHYYDGTI FHRSIRNFVI QGGDPTGTGT GGESYWGKPF KDEFRPNLSH TGRGILSMAN SGPNSNRSQF FITFRSCAYL DKKHTIFGRV VGGFDVLTAM ENVESDPKTD RPKEEIRIDA TTVFVDPYEE ADAQIAQERK TQLKVAPETK VKSSQPQAGS QGPQTFRQGV GKYINPAATE QQRKSPQPVP LSPCPRRSPV GVLGTSAPGS SRLPDDH.
    • 分子量62 kDa including tags
    • 氨基酸1 to 527
    • 标签His tag N-Terminus

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技术指标

Our Abpromise guarantee covers the use of ab117682 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity is > 300 nM/min/µg, and is defined as the amount of enzyme that cleave 1µM of suc-AAFP-pNA per minute at 1oC in Tris-HCl pH8.0 using chymotrypsin.
  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purified by proprietary chromatographic techniques
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • FLJ39930
    • CYC4
    • Cyclophilin 60
    • Cyclophilin 60kDa
    • Cyclophilin like protein Cyp 60
    • Cyclophilin-60
    • Cyclophilin-like protein Cyp-60
    • CYP60
    • hCyP 60
    • MGC33174
    • MGC787
    • Peptidyl prolyl cis trans isomerase like 2
    • Peptidyl-prolyl cis-trans isomerase-like 2
    • Peptidylprolyl cis trans isomerase
    • Peptidylprolyl isomerase cyclophilin like 2
    • PPIase
    • PPIL2
    • PPIL2_HUMAN
    • Rotamase
    • Rotamase PPIL2
    see all
  • 功能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • 组织特异性Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node (cortical, paracortical and medullar regions), thyroid (follicular epithelial cells), testis (developing spermatozoa), stomach (cells lining the gastric pit), pancreas, kidney (proximal and distal-tubule cells and collecting duct cells but not in glomeruli), endometrium and colon (goblet cells). Moderate protein expression in spleen, prostate (epithelium and squamous cell carcinomas), placenta and adrenal gland. Weak protein expression in liver, heart, breast, ovary, and lung. No protein expression in brain and bladder. High protein expression in most lymphomas and melanomas.
  • 序列相似性Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
    Contains 1 PPIase cyclophilin-type domain.
    Contains 1 U-box domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant human PPIL2 protein (ab117682)参考文献

ab117682 has not yet been referenced specifically in any publications.

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