This product is an active protein and may elicit a biological response in vivo, handle with caution.
Clk associating RS cyclophilin
Peptidyl prolyl cis trans isomerase G
Peptidyl prolyl isomerase G
Peptidyl-prolyl cis-trans isomerase G
Peptidyl-prolyl isomerase G
Peptidylprolyl isomerase G
Peptidylprolyl isomerase G (cyclophilin G)
SR related CTD associated factor 10
功能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.
序列相似性Contains 1 PPIase cyclophilin-type domain.
结构域The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
细胞定位Nucleus matrix. Nucleus speckle. Colocalizes with RNA splicing factors at nuclear speckles.