Recombinant人PPIG protein (ab117666)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ13427
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMGIKVQRPRCFFDIAINNQPAGRVVFELFS DVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFS EGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKP TPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCG
    • 分子量22 kDa including tags
    • 氨基酸1 to 175
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab117666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity is > 75 nmoles/min/ug, and is defined as the amount of enzyme that will cleave 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    ab117666 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明Although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.24% Tris, 0.02% DTT, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • CARS cyclophilin
    • CARS Cyp
    • CARS-cyclophilin
    • CARS-Cyp
    • CASP 10
    • CASP10
    • Clk associating RS cyclophilin
    • Clk-associating RS-cyclophilin
    • Cyclophilin G
    • CyclophilinG
    • CYP
    • MGC133241
    • Peptidyl prolyl cis trans isomerase G
    • Peptidyl prolyl isomerase G
    • Peptidyl-prolyl cis-trans isomerase G
    • Peptidyl-prolyl isomerase G
    • Peptidylprolyl isomerase G
    • Peptidylprolyl isomerase G (cyclophilin G)
    • PPIase G
    • Ppig
    • PPIG_HUMAN
    • Rotamase G
    • RotamaseG
    • SCAF10
    • SR cyclophilin
    • SR cyp
    • SR related CTD associated factor 10
    • SR-cyclophilin
    • SR-cyp
    • SRcyp
    see all
  • 功能PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.
  • 组织特异性Ubiquitous.
  • 序列相似性Contains 1 PPIase cyclophilin-type domain.
  • 结构域The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus matrix. Nucleus speckle. Colocalizes with RNA splicing factors at nuclear speckles.
  • Information by UniProt

Recombinant human PPIG protein (ab117666)参考文献

ab117666 has not yet been referenced specifically in any publications.

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