Recombinant人Plzf protein (ab125992)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ05516
    • 种属Human
    • 序列GELAVGMKSESRTIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCG KRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDM AVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLR SHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQ LETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEY CPSLSSMQKHMKGHKPEEIP
    • 氨基酸389 to 658

技术指标

Our Abpromise guarantee covers the use of ab125992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式Lyophilised
  • 补充说明For 50ug package, it is suggested to dissolve directly in 50ul DDW and the final concentration is 1.0ug/ul
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.2% Guanidine HCl

  • 复溶Reconstitute with water to desired concentration.

常规信息

  • 别名
    • AI467657
    • lu
    • PLZF
    • Promyelocytic leukemia zinc finger protein
    • ZBT16_HUMAN
    • ZBTB16
    • Zfp145
    • Zinc finger and BTB domain containing 16
    • zinc finger and BTB domain containing protein 16
    • Zinc finger and BTB domain-containing protein 16
    • Zinc finger protein 145
    • Zinc finger protein 145 (Kruppel like expressed in promyelocytic leukemia)
    • Zinc finger protein PLZF
    • Znf145
    see all
  • 功能Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 组织特异性Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
  • 通路Protein modification; protein ubiquitination.
  • 疾病相关Skeletal defects, genital hypoplasia, and mental retardation
    A chromosomal aberration involving ZBTB16 may be a cause of acute promyelocytic leukemia (APL). Translocation t(11;17)(q32;q21) with RARA.
  • 序列相似性Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 1 BTB (POZ) domain.
    Contains 9 C2H2-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human Plzf protein (ab125992)参考文献

ab125992 has not yet been referenced specifically in any publications.

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