Recombinant人PKN beta protein (ab125615)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ6P5Z2
    • 种属Human
    • 分子量130 kDa including tags
    • 氨基酸1 to 889
    • 标签GST tag N-Terminus

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技术指标

Our Abpromise guarantee covers the use of ab125615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity of ab125615 was determined to be 3 nmol/mg/min.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    ab204879 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • pkn3
    • PKN3_HUMAN
    • PKNBETA
    • Protein kinase C related kinase 3
    • Protein kinase N3
    • Protein kinase PKN beta
    • Protein kinase PKN-beta
    • Protein-kinase C-related kinase 3
    • RP11-545E17.1
    • Serine/threonine protein kinase N3
    • Serine/threonine-protein kinase N3
    see all
  • 功能Contributes to invasiveness in malignant prostate cancer.
  • 组织特异性Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
    Contains 3 REM (Hr1) repeats.
  • 结构域The C1 domain does not bind the diacylglycerol (DAG).
  • 翻译后修饰Autophosphorylated.
  • 细胞定位Nucleus. Cytoplasm > perinuclear region. Nuclear and perinuclear Golgi region.
  • Information by UniProt

Recombinant human PKN beta protein 图像

  • Sample Kinase Assay showing the specific activity of ab125615 as 3 nmol/mg/min.
  • SDS-PAGE analysis of ab125615.

Recombinant human PKN beta protein (ab125615)参考文献

ab125615 has not yet been referenced specifically in any publications.

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Thank you for contacting us.
I regret to inform you that the immunogen sequence homology between rat and human is only 22% so this antibody should not be cross reacting with rat protein. I apologize for an inconvenience.
This is the only produ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"