概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSS KHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFT SQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR ERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKS FPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLN NLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS FGYASVQNPASNLSACQYAVDRPV
    • 氨基酸
      1 to 324
    • 标签
      proprietary tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab152611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • All1 responsive gene 1
    • ALL1 responsive protein ARP1
    • ALL1-responsive protein ARP1
    • ARP 1
    • ARP1
    • Brx 1
    • Brx1
    • Homeobox protein PITX2
    • IDG 2
    • IDG2
    • IGDS
    • IGDS 2
    • IGDS2
    • IHG 2
    • IHG2
    • IRID 2
    • IRID2
    • MGC111022
    • MGC20144
    • Otlx 2
    • Otlx2
    • Paired like homeodomain transcription factor 2
    • Paired-like homeodomain transcription factor 2
    • Pituitary homeo box 2
    • Pituitary homeobox 2
    • PITX 2
    • pitx2
    • PITX2_HUMAN
    • PTX 2
    • PTX2
    • RGS
    • RIEG
    • RIEG 1
    • RIEG bicoid related homeobox transcription factor
    • Rieg bicoid related homeobox transcription factor 1
    • RIEG bicoid-related homeobox transcription factor
    • RIEG1
    • RS
    • Solurshin
    see all
  • 功能
    May play an important role in development and maintenance of anterior structures. Isoform PTX2C is involved in left-right asymmetry the developing embryo.
  • 疾病相关
    Defects in PITX2 are the cause of Axenfeld-Rieger syndrome type 1 (RIEG1) [MIM:180500]; also known as Rieger syndrome type 1. RIEG1 is an autosomal dominant defect characterized by hypodontia (partial anodontia), anal stenosis, hypertelorism, mental deficiency, agenesis of the facial bones, with malformation of the anterior chamber of the eye.
    Defects in PITX2 are the cause of iridogoniodysgenesis type 2 (IRID2) [MIM:137600]; also known as iridogoniodysgenesis syndrome 2 (IGDS2). It is an autosomal dominant inherited disease.
    Defects in PITX2 are a cause of Peters anomaly (PAN) [MIM:604229]. It is a congenital defect of the anterior chamber of the eye.
    Defects in PITX2 are associated with ring dermoid of cornea (RDC) [MIM:180550]. RDC is an autosomal dominantly inherited syndrome characterized by bilateral annular limbal dermoids with corneal and conjunctival extension.
  • 序列相似性
    Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • ab152611 on a 12.5% SDS-PAGE stained with Coomassie Blue.

文献

ab152611 has not yet been referenced specifically in any publications.

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