Recombinant人PITX1 protein (ab114745)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVY RDTCNSSLASLRLKSKQHSSFGYGALQGPASGLNACQYN
    • 分子量
      35 kDa including tags
    • 氨基酸
      225 to 313

技术指标

Our Abpromise guarantee covers the use of ab114745 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BFT
    • CCF
    • Hindlimb expressed homeobox protein backfoot
    • Hindlimb-expressed homeobox protein backfoot
    • Homeobox protein PITX1
    • LBNBG
    • Paired like homeodomain 1
    • Paired like homeodomain transcription factor 1
    • Paired-like homeodomain transcription factor 1
    • Pituitary homeo box 1
    • Pituitary homeobox 1
    • Pituitary otx related factor
    • Pitx1
    • PITX1_HUMAN
    • POTX
    • PTX1
    see all
  • 功能
    May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
  • 疾病相关
    Defects in PITX1 are a cause of congenital clubfoot (CCF) [MIM:119800]; also known as talipes equinovarus (TEV). Clubfoot is a congenital limb deformity defined as fixation of the foot in cavus, adductus, varus, and equinus (i.e. inclined inwards, axially rotated outwards, and pointing downwards) with concomitant soft tissue abnormalities. Clubfoot may occur in isolation or as part of a syndrome. Clubfoot appears to be a multifactorial trait.
  • 序列相似性
    Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt

Recombinant Human PITX1 protein 图像

  • 12.5% SDS-PAGE showing ab114745 at approximately 35.42kDa.
    Stained with Coomassie Blue.

Recombinant Human PITX1 protein (ab114745)参考文献

ab114745 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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