Recombinant人PITX1 protein (ab114744)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP78337
    • 种属Human
    • 序列MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASES SDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERN QQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFT FFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTG SSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGAL QGPASGLNACQYNS
    • 分子量61 kDa including tags
    • 氨基酸1 to 314

技术指标

Our Abpromise guarantee covers the use of ab114744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • BFT
    • CCF
    • Hindlimb expressed homeobox protein backfoot
    • Hindlimb-expressed homeobox protein backfoot
    • Homeobox protein PITX1
    • LBNBG
    • Paired like homeodomain 1
    • Paired like homeodomain transcription factor 1
    • Paired-like homeodomain transcription factor 1
    • Pituitary homeo box 1
    • Pituitary homeobox 1
    • Pituitary otx related factor
    • Pitx1
    • PITX1_HUMAN
    • POTX
    • PTX1
    see all
  • 功能May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
  • 疾病相关Defects in PITX1 are a cause of congenital clubfoot (CCF) [MIM:119800]; also known as talipes equinovarus (TEV). Clubfoot is a congenital limb deformity defined as fixation of the foot in cavus, adductus, varus, and equinus (i.e. inclined inwards, axially rotated outwards, and pointing downwards) with concomitant soft tissue abnormalities. Clubfoot may occur in isolation or as part of a syndrome. Clubfoot appears to be a multifactorial trait.
  • 序列相似性Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human PITX1 protein 图像

  • 12.5% SDS-PAGE showing ab114744 at approximately 60.61kDa.
    Stained with Coomassie Blue.

Recombinant Human PITX1 protein (ab114744)参考文献

ab114744 has not yet been referenced specifically in any publications.

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