概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      NACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALER HFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLF SISKEHLECR
    • 分子量
      38 kDa including tags
    • 氨基酸
      182 to 291

相关产品

技术指标

Our Abpromise guarantee covers the use of ab152622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Dwarf
    • GHF 1
    • GHF 1A
    • GHF-1
    • GHF1
    • GHF1A
    • Growth hormone factor 1
    • Hmp 1
    • Hmp1
    • Pit 1
    • Pit 1 beta
    • PIT 1Z
    • PiT-1
    • Pit1 beta
    • PIT1_HUMAN
    • PIT1Z
    • Pituitary growth hormone
    • Pituitary specific positive transcription factor 1
    • Pituitary-specific positive transcription factor 1
    • POU class 1 homeobox 1
    • POU domain class 1 transcription factor 1
    • POU domain transcriptional regulator
    • POU1F1
    see all
  • 功能
    Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.
  • 疾病相关
    Defects in POU1F1 are the cause of pituitary hormone deficiency combined type 1 (CPHD1) [MIM:613038]. CPHD is characterized by impaired production of growth hormone (GH) and one or more of the other five anterior pituitary hormones.
  • 序列相似性
    Belongs to the POU transcription factor family. Class-1 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab152622 stained with Coomassie Blue.

文献

ab152622 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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