This product is an active protein and may elicit a biological response in vivo, handle with caution.
Phosphatidylinositol 4 kinase type 2 alpha
Phosphatidylinositol 4 kinase type II alpha
Together with PI4K2B and the type III PI4Ks (PIK4CA and PIK4CB) PI4K2A contributes to the overall PI4 kinase activity of the cell. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells
Cytoplasm. Membrane. Note: Found in subdomains of the plasma membrane termed non caveolar membrane rafts.
SDS-PAGE - PI4K2A protein (Active) (ab102109)
ab102109 was determined to be >95% pure as assessed by densitometry. The predicted molecular weight is ~79 kDa.
Functional Studies - PI4K2A protein (Active) (ab102109)
ab102109 has a specific activity of 95 nmol/min/mg.
has not yet been referenced specifically in any publications.