重组人PI4 kinase beta蛋白(ab152609)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MRFLEARSLAVAMGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVG ELSVIDPEVAQKACQEVLEKVKLLHGGVAVSSRGTPLELVNGDGVDSEIR CLDDPPAQIREEEDEMGAAVASGTAKGARRRRQNNSAKQSWLLRLFESKL FDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDE DVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRK LILSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSN LKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKR LATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVV LNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPECGIT HEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVD SITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQ EKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQ ERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEH GSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHI DFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLI AARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLL VEQMVDGSMRSITTKLYDGFQYLTNGIM
    • 氨基酸
      1 to 828
    • 标签
      proprietary tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab152609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • DKFZp686O1820
    • FLJ30129
    • NPIK
    • Phosphatidylinositol 4 kinase beta
    • Phosphatidylinositol 4 kinase catalytic beta
    • Phosphatidylinositol 4 kinase catalytic beta polypeptide
    • Phosphatidylinositol 4 kinase wortmannin sensitive
    • Phosphatidylinositol 4-kinase beta
    • PI4K BETA
    • PI4K-beta
    • PI4K92
    • PI4KB
    • PI4KB_HUMAN
    • PI4Kbeta
    • PI4KIIIbeta
    • PIK4CB
    • PtdIns 4 kinase
    • PtdIns 4-kinase beta
    • Type III phosphatidylinositol 4 kinase beta
    see all
  • 功能
    Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • 组织特异性
    Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
  • 序列相似性
    Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
    Contains 1 PI3K/PI4K domain.
    Contains 1 PIK helical domain.
  • 细胞定位
    Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
  • Information by UniProt

图片

  • ab152609 on a 12.5% SDS-PAGE stained with Coomassie Blue.

文献

ab152609 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab152609.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册