This product is an active protein and may elicit a biological response in vivo, handle with caution.
PHK gamma M
Phosphorylase b kinase gamma catalytic chain
Phosphorylase b kinase gamma catalytic chain skeletal muscle/heart isoform
phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform
phosphorylase kinase gamma
phosphorylase kinase subunit gamma 1
Phosphorylase kinase subunit gamma-1
phosphorylase kinase, gamma 1 (muscle)
Phosphorylase kinase, muscle, gamma-1
Serine/threonine-protein kinase PHKG1
skeletal muscle/heart isoform
功能Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3.
序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Contains 1 protein kinase domain.
结构域The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.