Recombinant人PGP9.5 protein (ab82628)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab82628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50mM Tris, 10mM GSH, pH 8

  • 复溶Packaging size : 0.1 mg

常规信息

  • 别名
    • Epididymis luminal protein 117
    • Epididymis secretory protein Li 53
    • HEL 117
    • HEL S 53
    • NDGOA
    • Neuron cytoplasmic protein 9.5
    • OTTHUMP00000218137
    • OTTHUMP00000218139
    • OTTHUMP00000218140
    • OTTHUMP00000218141
    • Park 5
    • PARK5
    • PGP 9.5
    • PGP9.5
    • PGP95
    • Protein gene product 9.5
    • Ubiquitin C terminal esterase L1
    • Ubiquitin C terminal hydrolase
    • Ubiquitin C terminal hydrolase L1
    • Ubiquitin carboxyl terminal esterase L1
    • Ubiquitin carboxyl terminal hydrolase isozyme L1
    • Ubiquitin carboxyl-terminal hydrolase isozyme L1
    • Ubiquitin thioesterase L1
    • Ubiquitin thiolesterase
    • Ubiquitin thiolesterase L1
    • UCH-L1
    • UCHL1
    • UCHL1_HUMAN
    see all
  • 功能Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
  • 组织特异性Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
  • 疾病相关Parkinson disease 5
    Neurodegeneration with optic atrophy, childhood-onset
  • 序列相似性Belongs to the peptidase C12 family.
  • 翻译后修饰O-glycosylated.
  • 细胞定位Cytoplasm. Endoplasmic reticulum membrane. About 30% of total UCHL1 is associated with membranes in brain.
  • Information by UniProt

Recombinant Human PGP9.5 protein 图像

  • ab82628 at 1µg on SDS-PAGE.

Recombinant Human PGP9.5 protein (ab82628)参考文献

ab82628 has not yet been referenced specifically in any publications.

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