Recombinant人Peroxiredoxin 4 protein (ab117192)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ13162
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MWETEERPRT REEECHFYAG GQVYPGEASR VSVADHSLHL SKAKISKPAP YWEGTAVIDG EFKELKLTDY RGKYLVFFFY PLDFTFVCPT EIIAFGDRLE EFRSINTEVV ACSVDSQFTH LAWINTPRRQ GGLGPIRIPL LSDLTHQISK DYGVYLEDSG HTLRGLFIID DKGILRQITL NDLPVGRSVD ETLRLVQAFQ YTDKHGEVCP AGWKPGSETI IPDPAGKLKY FDKLN
    • 分子量29 kDa including tags
    • 氨基酸38 to 271
    • 标签His tag N-Terminus
    • 额外的序列信息PRDX4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 255 amino acids (38-271 a.a.).

技术指标

Our Abpromise guarantee covers the use of ab117192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: approximately 230-310 pmole/min/µg.
    Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX4 and peroxide for 20 min at room temperature.
    Specific activity is defined as the amount of hydroperoxide that 1µg of enzyme can reduce at 25°C for 1 minute.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • 补充说明Should be stored desiccated.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 10% Glycerol, 0.32% Tris HCl

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Antioxidant enzyme 372
    • Antioxidant enzyme AOE372
    • AOE37 2
    • AOE37-2
    • AOE372
    • EC 1.11.1.15
    • Peroxiredoxin IV
    • Peroxiredoxin-4
    • Peroxiredoxin4
    • PRDX 4
    • Prdx4
    • PRDX4_HUMAN
    • PRX 4
    • Prx IV
    • Prx-IV
    • PRX4
    • PrxIV
    • Thioredoxin dependent peroxide reductase A0372
    • Thioredoxin peroxidase
    • Thioredoxin Peroxidase (Antioxidant Enzyme)
    • Thioredoxin peroxidase AO372
    • Thioredoxin-dependent peroxide reductase A0372
    • TRANK
    see all
  • 功能Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
  • 序列相似性Belongs to the ahpC/TSA family.
    Contains 1 thioredoxin domain.
  • 细胞定位Cytoplasm. Secreted.
  • Information by UniProt

Recombinant human Peroxiredoxin 4 protein (ab117192)参考文献

ab117192 has not yet been referenced specifically in any publications.

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