Add 0.2 ml of 0.1M Acetate buffer pH4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10µg/ml. In higher concentrations the solubility of this antigen is limited.
Osteoblast specific factor
Osteoblast specific factor 2
Osteoblast specific factor 2 (fasciclin I like)
Osteoblast-specific factor 2
Periodontal ligament specific periostin
Periostin isoform thy2
Periostin isoform thy4
Periostin isoform thy6
Periostin isoform thy8
Periostin osteoblast specific factor
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers.
Contains 1 EMI domain. Contains 4 FAS1 domains.
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
Secreted > extracellular space > extracellular matrix.