Recombinant人Pea3 protein (ab114394)

概述

  • 产品名称Recombinant人Pea3 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP43268
    • 种属Human
    • 序列MYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDDVCVAPEKFEGDIKQEGVG AFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEV ARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEAL FSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFG PKGGYSY
    • 分子量49 kDa including tags
    • 氨基酸278 to 484

技术指标

Our Abpromise guarantee covers the use of ab114394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    ab114394 is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • Adenovirus E1A enhancer binding protein
    • Adenovirus E1A enhancer-binding protein
    • E1A F
    • E1A-F
    • ETS translocation variant 4
    • ets variant gene 4 (E1A enhancer binding protein E1AF)
    • ETV4
    • ETV4_HUMAN
    • PEA3
    • PEA3 protein
    • PEAS3
    • Polyomavirus enhancer activator 3
    • Polyomavirus enhancer activator 3 homolog
    • Protein PEA3
    see all
  • 功能Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
  • 序列相似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 翻译后修饰Sumoylated; enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human Pea3 protein 图像

  • ab114394 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human Pea3 protein (ab114394)参考文献

ab114394 has not yet been referenced specifically in any publications.

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