Recombinant人PDK2 protein (ab125592)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ15119
    • 种属Human
    • 分子量70 kDa including tags
    • 氨基酸1 to 407

技术指标

Our Abpromise guarantee covers the use of ab125592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity of ab125592 was determined to be 7.5 nmol/min/mg.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    ab125602 (Human Pyruvate Dehydrogenase E1-alpha subunit full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2
    • mitochondrial
    • PDHK2
    • PDK2
    • PDK2_HUMAN
    • Pyruvate dehydrogenase kinase isoform 2
    • Pyruvate dehydrogenase kinase, isozyme 2
    • Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial
    see all
  • 功能Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
  • 组织特异性Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung.
  • 序列相似性Belongs to the PDK/BCKDK protein kinase family.
    Contains 1 histidine kinase domain.
  • 细胞定位Mitochondrion matrix.
  • Information by UniProt

Recombinant human PDK2 protein 图像

  • SDS Page analysis of ab125592
  • The specific activity of ab125592 was determined to be 7.5 nmol/min/mg

Recombinant human PDK2 protein (ab125592)参考文献

ab125592 has not yet been referenced specifically in any publications.

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