Recombinant人PDGFAA + PDGFBB protein (ab61903)

概述

  • 产品名称Recombinant人PDGFAA + PDGFBB protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列alpha chain:-MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT beta chain:- MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIGIVR KKPIFKKATV TLGDHLACKC ETVAAARPVT

技术指标

Our Abpromise guarantee covers the use of ab61903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Biological Activity: The activity is determined by the dose-dependent proliferation of mouse 3T3 indicator cells and is typically less than 1 ng/mL.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    Purity greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
  • 形式Lyophilised
  • 补充说明It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
  • Concentration information loading...

制备和贮存

  • 稳定性��存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10mM Acetic acid

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.

常规信息

  • 别名
    • becaplermin
    • c-sis
    • FLJ12858
    • PDGF 1
    • PDGF 2
    • PDGF B
    • PDGF B chain
    • PDGF subunit B
    • PDGF-2
    • Pdgfb
    • PDGFB_HUMAN
    • Platelet derived growth factor beta polypeptide
    • platelet-derived growth factor 2
    • Platelet-derived growth factor B chain
    • Platelet-derived growth factor beta polypeptide
    • Platelet-derived growth factor subunit B
    • Platelet-derived growth factor, beta polypeptide (oncogene SIS)
    • Proto-oncogene c-Sis
    • SIS
    • SSV
    see all
  • 功能Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • 组织特异性Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
  • 疾病相关Note=A chromosomal aberration involving PDGFB is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF.
  • 序列相似性Belongs to the PDGF/VEGF growth factor family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human PDGFAA + PDGFBB protein 图像

  • ab61903 used in Western Blot. Figure: 1 ug in each lane (-) non-reducing conditions and (+) reducing conditions in a 4-20% Tris-Glycine gel stained with Coomassie Blue. Human PDGF-AB is predicted to be a disulfide linked heterodimer with a predicted MW of 25.5 kDa.

Recombinant human PDGFAA + PDGFBB protein (ab61903)参考文献

ab61903 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab61903.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"