This product is an active protein and may elicit a biological response in vivo, handle with caution.
cAMP specific 3 5 cyclic phosphodiesterase 7B
cAMP specific 3'5' cyclic phosphodiesterase 7B
High affinity cAMP specific 3 5 cyclic phosphodiesterase
High affinity cAMP specific 3'5' cyclic phosphodiesterase
Rolipram insensitive phosphodiesterase type 7
PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis.
PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
SDS-PAGE - PDE7B protein (ab101593)
SDS-PAGE analysis of ab101593
Functional Studies - PDE7B protein (ab101593)
Specific activity of ab101593
has not yet been referenced specifically in any publications.