Recombinant人PDE6C protein (ab116895)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP51160
    • 种属Human
    • 序列EINQVAVEKYLEENPQFAKEYFDRKLRVEVLGEIFKNSQVPVQSSMSFSE LTQVEESALCLELLWTVQEEGGTPEQGVHRALQRLAHLLQADRCSMFL
    • 分子量36 kDa including tags
    • 氨基酸3 to 100

技术指标

Our Abpromise guarantee covers the use of ab116895 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • 5''-cyclic phosphodiesterase subunit alpha''
    • cGMP phosphodiesterase 6C
    • COD4
    • Cone cGMP specific 3' 5' cyclic phosphodiesterase subunit alpha'
    • Cone cGMP-specific 3''
    • PDE 6C
    • PDE6 alpha prime
    • PDE6 alpha'
    • PDE6C
    • PDE6C_HUMAN
    • PDEA2
    • Phosphodiesterase 6C cGMP specific cone alpha prime
    see all
  • 疾病相关Defects in PDE6C are the cause of cone dystrophy type 4 (COD4) [MIM:613093]. An early-onset cone dystrophy. Cone dystrophies are retinal dystrophies characterized by progressive degeneration of the cone photoreceptors with preservation of rod function, as indicated by electroretinogram. However, some rod involvement may be present in some cone dystrophies, particularly at late stage. Affected individuals suffer from photophobia, loss of visual acuity, color vision and central visual field. Another sign is the absence of macular lesions for many years. Cone dystrophies are distinguished from the cone-rod dystrophies in which some loss of peripheral vision also occurs.
  • 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family.
    Contains 2 GAF domains.
  • 细胞定位Cell membrane.
  • Information by UniProt

Recombinant Human PDE6C protein 图像

  • 12.5% SDS-PAGE showing ab116895 at approximately 36.41kDa stained with Coomassie Blue.

Recombinant Human PDE6C protein (ab116895)参考文献

ab116895 has not yet been referenced specifically in any publications.

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