Recombinant人PDE4B protein (ab125582)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ07343
    • 种属Human
    • 分子量78 kDa including tags
    • 氨基酸305 to 736
    • 标签GST tag N-Terminus

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技术指标

Our Abpromise guarantee covers the use of ab125582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity of ab125582 was determined to be 538 nmol/min/mg.
  • 应用

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • 5''-cyclic phosphodiesterase 4B
    • cAMP-specific 3''
    • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    • cAMP-specific phosphodiesterase-4 B isoform
    • DKFZp686F2182
    • DPDE4
    • dunce-like phosphodiesterase E4
    • MGC126529
    • OTTHUMP00000010652
    • OTTHUMP00000010653
    • OTTHUMP00000010654
    • OTTHUMP00000010656
    • OTTHUMP00000232365
    • PDE 4B
    • PDE IVB
    • PDE32
    • Pde4b
    • PDE4B_HUMAN
    • PDE4B5
    • PDEIVB
    • Phosphodiesterase 4B
    • Phosphodiesterase 4B cAMP specific
    • Phosphodiesterase 4B, cAMP specific (phosphodiesterase E4 dunce homolog, Drosophila)
    see all
  • 功能Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
  • 组织特异性Expressed in brain, heart, lung and skeletal muscle.
  • 通路Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt

Recombinant human PDE4B protein 图像

  • SDS Page analysis of ab125582
  • The specific activity of ab125582 was determined to be 538 nmol/min/mg.

Recombinant human PDE4B protein (ab125582)参考文献

ab125582 has not yet been referenced specifically in any publications.

Product Wall

I apologize for the delay in my reply.

The protein sequence associated with this product is found at the catalytic domain of the protein.

I hope this is helpful. Please contact us again if you have any further questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"