Recombinant人PDE2A protein (ab114923)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO00408
    • 种属Human
    • 序列REKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS HKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDA
    • 分子量36 kDa including tags
    • 氨基酸850 to 940

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技术指标

Our Abpromise guarantee covers the use of ab114923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris buffered saline, 0.3% Glutathione

常规信息

  • 别名
    • 5''-cyclic phosphodiesterase
    • cGMP dependent 3'5' cyclic phosphodiesterase
    • cGMP stimulated phosphodiesterase 1
    • cGMP stimulated phosphodiesterase 4
    • cGMP-dependent 3''
    • cGMP-stimulated phosphodiesterase 2
    • CGS PDE
    • CGS-PDE
    • cGSPDE
    • Cyclic GMP stimulated phosphodiesterase
    • Cyclic GMP-stimulated phosphodiesterase
    • Human cGMP stimulated 3'5' cyclic nucleotide phosphodiesterase
    • PDE 2A
    • PDE 2A1
    • PDE 2A4
    • PDE2A
    • PDE2A_HUMAN
    • PDE2A1
    • PDE2A4
    • phosphodiesterase 2A
    • Phosphodiesterase 2A cGMP stimulated
    see all
  • 功能Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
  • 组织特异性Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
    Contains 2 GAF domains.
  • 结构域GAF 1 functions as a dimerization domain, whereas GAF 2 binds cGMP, which causes activation of the catalytic activity of the enzyme.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human PDE2A protein 图像

  • 12.5% SDS-PAGE showing ab114923 at approximately 35.64kDa.
    Stained with Coomassie Blue.

Recombinant Human PDE2A protein (ab114923)参考文献

ab114923 has not yet been referenced specifically in any publications.

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