- 来源Wheat germ
- 序列REKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS HKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDA
- 分子量36 kDa including tags
- 氨基酸850 to 940
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 补充说明Protein concentration is above or equal to 0.05 mg/ml.
This protein is best used within three months from the date of receipt.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.79% Tris buffered saline, 0.3% Glutathione
- 5''-cyclic phosphodiesterase
- cGMP dependent 3'5' cyclic phosphodiesterase
- cGMP stimulated phosphodiesterase 1
- 功能Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
- 组织特异性Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
- 序列相似性Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
- 结构域GAF 1 functions as a dimerization domain, whereas GAF 2 binds cGMP, which causes activation of the catalytic activity of the enzyme.
Information by UniProt
Recombinant Human PDE2A protein 图像
Recombinant Human PDE2A protein (ab114923)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"