Recombinant人PDCD6 protein (ab104605)

概述

  • 产品名称Recombinant人PDCD6 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO75340
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMAAYSYRPGPGAGPGPAAGAALPDQSFLWN VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV NFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQF HDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY EQYLSMVFSIV
    • 分子量24 kDa including tags
    • 氨基酸1 to 191
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab104605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    ab104605 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 10mM Sodium citrate, pH 3.5

常规信息

  • 别名
    • AIP1
    • ALG 2
    • ALG-2-interacting protein 1
    • ALG2
    • ALIX
    • Apoptosis linked gene 2
    • Apoptosis linked gene 2 protein
    • Apoptosis-linked gene 2 protein
    • FLJ42309
    • FLJ46208
    • Hp95
    • KIAA1375
    • MA 3
    • MA3
    • MGC111017
    • MGC119050
    • MGC9123
    • PDCD 6
    • Pdcd6
    • PDCD6_HUMAN
    • PEF 1B
    • PEF1B
    • Probable calcium binding protein ALG 2
    • Probable calcium binding protein ALG2
    • Probable calcium-binding protein ALG-2
    • Programmed cell death 6
    • Programmed cell death 6-interacting protein
    • Programmed cell death protein 6
    • PS 2
    • PS2
    see all
  • 功能Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
  • 序列相似性Contains 5 EF-hand domains.
  • 细胞定位Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
  • Information by UniProt

Recombinant Human PDCD6 protein 图像

  • 15% SDS-PAGE showing ab104605 (3 µg) at approximately 24 kDa.

Recombinant Human PDCD6 protein (ab104605)参考文献

ab104605 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"