Recombinant人PAX7 protein (ab114237)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP23759
    • 种属Human
    • 序列GGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTTGYSVDPVAGY QYGQYGQSECLVPWASPVPIPSPTPRASCLFMESYKVVSGWGMSISQMEK LKSSQMEQFT
    • 分子量38 kDa including tags
    • 氨基酸411 to 521

技术指标

Our Abpromise guarantee covers the use of ab114237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • FLJ37460
    • HUP1
    • OTTHUMP00000002534
    • Paired box 7
    • Paired box gene 7
    • Paired box homeotic gene 7
    • Paired box protein Pax-7
    • Paired domain gene 7
    • Paired domain gene HuP1
    • Pax7
    • PAX7 transcriptional factor
    • PAX7/FKHR fusion gene, included
    • PAX7_HUMAN
    • PAX7B
    • RGD1564360
    • RMS2
    see all
  • 功能Probable transcription factor. May have a role in myogenesis.
  • 疾病相关Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
  • 序列相似性Belongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 paired domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human PAX7 protein 图像

  • 12.5% SDS-PAGE showing ab114237 at approximately 38.21kDa stained with Coomassie Blue.

Recombinant Human PAX7 protein (ab114237)参考文献

ab114237 has not yet been referenced specifically in any publications.

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