Recombinant人PARP9 protein (ab79665)

概述

  • 产品名称
    Recombinant人PARP9 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属
      Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab79665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Specific Activity: 196 U/mg.
  • 应用

    SDS-PAGE

    Functional Studies

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • ADP-ribosyltransferase diphtheria toxin-like 9
    • ARTD9
    • AW214463
    • B aggressive lymphoma protein
    • Bagl
    • BAL
    • BAL1
    • BC003281
    • DKFZp666B0810
    • DKFZp686M15238
    • EC 2.4.2.30
    • FLJ26637
    • FLJ35310
    • FLJ41418
    • FLJ43593
    • MGC:7868
    • MGC156739
    • MGC7868
    • OTTMUSP00000028034
    • PARP 9
    • PARP-9
    • Parp9
    • PARP9_HUMAN
    • Poly (ADP ribose) polymerase family member 9
    • Poly [ADP-ribose] polymerase 9
    • RGD1307534
    see all
  • 功能
    Involved in inducing the expression of IFN-gamma-responsive genes.
  • 组织特异性
    Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.
  • 疾病相关
    Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.
  • 序列相似性
    Contains 2 Macro domains.
    Contains 1 PARP catalytic domain.
  • 细胞定位
    Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.
  • Information by UniProt

图片

  • SDS-PAGE showing ab79665 at approximately 119kDa (4µg).

文献

ab79665 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for contacting us.

The lab let me know that the protein is a (proprietary tag)-PARP9-His. It has the proprietary tag on the N-terminus and a C-terminal 6x His-tag.

I hope this helps explain your results.

Please...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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