Recombinant人PARP9 protein (ab79665)

概述

  • 产品名称Recombinant人PARP9 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab79665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific Activity: 196 U/mg.
  • 应用

    SDS-PAGE

    Functional Studies

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • ADP-ribosyltransferase diphtheria toxin-like 9
    • ARTD9
    • AW214463
    • B aggressive lymphoma protein
    • Bagl
    • BAL
    • BAL1
    • BC003281
    • DKFZp666B0810
    • DKFZp686M15238
    • EC 2.4.2.30
    • FLJ26637
    • FLJ35310
    • FLJ41418
    • FLJ43593
    • MGC:7868
    • MGC156739
    • MGC7868
    • OTTMUSP00000028034
    • PARP 9
    • PARP-9
    • Parp9
    • PARP9_HUMAN
    • Poly (ADP ribose) polymerase family member 9
    • Poly [ADP-ribose] polymerase 9
    • RGD1307534
    see all
  • 功能Involved in inducing the expression of IFN-gamma-responsive genes.
  • 组织特异性Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.
  • 疾病相关Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.
  • 序列相似性Contains 2 Macro domains.
    Contains 1 PARP catalytic domain.
  • 细胞定位Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.
  • Information by UniProt

Recombinant human PARP9 protein 图像

  • SDS-PAGE showing ab79665 at approximately 119kDa (4µg).

Recombinant human PARP9 protein (ab79665)参考文献

ab79665 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The lab let me know that the protein is a (proprietary tag)-PARP9-His. It has the proprietary tag on the N-terminus and a C-terminal 6x His-tag.

I hope this helps explain your results.

Please...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"