Recombinant人PAPSS1 protein (ab123177)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO43252
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSHMRATNV TYQAHHVSRN KRGQVVGTRG GFRGCTVWLT GLSGAGKTTV SMALEEYLVC HGIPCYTLDG DNIRQGLNKN LGFSPEDREE NVRRIAEVAK LFADAGLVCI TSFISPYTQD RNNARQIHEG ASLPFFEVFV DAPLHVCEQR DVKGLYKKAR AGEIKGFTGI DSEYEKPEAP ELVLKTDSCD VNDCVQQVVE LLQERDIVPV DASYEVKELY VPENKLHLAK TDAETLPALK INKVDMQWVQ VLAEGWATPL NGFMREREYL QCLHFDCLLD GGVINLSVPI VLTATHEDKE RLDGCTAFAL MYEGRRVAIL RNPEFFEHRK EERCARQWGT TCKNHPYIKM VMEQGDWLIG GDLQVLDRVY WNDGLDQYRL TPTELKQKFK DMNADAVFAF QLRNPVHNGH ALLMQDTHKQ LLERGYRRPV LLLHPLGGWT KDDDVPLMWR MKQHAAVLEE GVLNPETTVV AIFPSPMMYA GPTEVQWHCR ARMVAGANFY IVGRDPAGMP HPETGKDLYE PSHGAKVLTM APGLITLEIV PFRVAAYNKK KKRMDYYDSE HHEDFEFISG TRMRKLAREG QKPPEGFMAP KAWTVLTEYY KSLEKA
    • 分子量71 kDa including tags
    • 氨基酸24 to 624
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 85 % SDS-PAGE.
    ab123177 is purified using conventional chromatography.
  • 形式Liquid
  • 补充说明Additional E.C. Number: =2.7.7.4
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1
    • 3' phosphoadenosine 5' phosphosulfate synthase 1
    • 3''-phosphoadenosine-5''-phosphosulfate synthase
    • Adenosine-5''-phosphosulfate 3''-phosphotransferase
    • Adenylyl-sulfate kinase
    • Adenylylsulfate 3''-phosphotransferase
    • APS kinase
    • ATP-sulfurylase
    • ATPSK 1
    • ATPSK1
    • ATPSK2
    • Bifunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1
    • PAPS synthase 1
    • PAPS synthetase 1
    • PAPS1_HUMAN
    • PAPSS
    • PAPSS 1
    • PAPSS1
    • SAT
    • SK 1
    • SK1
    • SK2
    • Sulfate adenylate transferase
    • Sulfurylase kinase 1
    see all
  • 功能Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
  • 组织特异性Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage.
  • 通路Sulfur metabolism; sulfate assimilation.
  • 序列相似性In the N-terminal section; belongs to the APS kinase family.
    In the C-terminal section; belongs to the sulfate adenylyltransferase family.
  • Information by UniProt

Recombinant Human PAPSS1 protein 图像

  • 15% SDS-PAGE analysis of ab123177 (3ug)

Recombinant Human PAPSS1 protein (ab123177)参考文献

ab123177 has not yet been referenced specifically in any publications.

Product Wall


The lab let me know that the protein’s biological activity hasn’t been tested yet.
But the protein hasn’t been exposed to denaturing agents, so it is possible that it’s bioactive.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"